Is Aging Impacted by Changes in Gut Microbiome?
Is Aging Impacted by Changes in Gut Microbiome? Aging is an underlying risk factor for various diseases. Gut microbiome plays an vital role in the development of chronic diseases. The human digestive tract is inhabited by various microorganisms. Gut microbiotas of healthy adults are stable even for decades. In life even within 2 years after birth ,the gut microbiota seems to be maintained stable. Many compounds, either endogenous or exogenous, are known to modulate health and lifespan. Marmosets (small monkeys that live high up in the canopies of South American rainforests) are unique animal models that provides researchers an opportunity to estimate the relationship between changes in gut health and age-related health outcomes. With advancing age, the gut microbiota becomes more diverse and variable. Gut dysbiosis can trigger the innate immune response and chronic inflammation , resulting in unhealthy aging. The gut microbiota transmits with the host through various bio...